ACL Feasibility Study Could Revolutionize Treatment for Osteoarthritis

A team of researchers at the Hospital for Special Surgery in New York City, Mayo Clinic in Rochester, Minnesota and the University of California, San Francisco (UCSF) are using an Arthritis Foundation award to demonstrate the feasibility of using state-of-the-art technologies to monitor joint health after ACL injuries across multiple research centers. The team is testing the ability of new magnetic resonance imaging (MRI) techniques to measure the molecular changes that begin to occur immediately after an ACL tear. The study will demonstrate the feasibility of using these MRI techniques in clinical trials of components that can potentially treat OA.

“Not everyone who has an ACL tear will develop osteoarthritis, but some do,” says Dr. Scott Rodeo, Orthopedic Surgeon at Hospital for Special Surgery and project co-principal investigator. The goal is to identify biomarkers that reflect alterations in the joint environment that may be predictive of developing arthritis.”

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