Febuxostat
Drug Class: Uric acid (Xanthine oxidase inhibitor)
Brand Names: Uloric
Dosages
40 to 80 mg daily. Dose may be adjusted to achieve a blood uric acid level lower than 6 mg/dL.
Potential Side Effects
Gout flares; joint pain; liver function problems; nausea; rash.
Special Instructions
Never start or stop this drug during a flare.
Be Aware
Do not take febuxostat if you also take azathioprine, mercaptopurine or theophylline. Your doctor may order blood tests to check your liver function while you are taking this medication. Acute gout attacks are common when this drug is started. These attacks may be reduced by gradually increasing the dose and taking an anti-inflammatory medication for the first 6 to 12 months of therapy. The medicine has been linked to a possible increased risk of heart attack and stroke.
LAST UPDATED: 03/27/2014