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Last Updated: 12/23/2024

Cyclobenzaprine

Drug Name(s): Amrix, Fexmid, generic

Class: Muscle relaxants

Used off-label to treat muscle pain and insomnia associated with fibromyalgia.

Dosage

Form(s): tablet, extended-release capsule 

5 mg to 30 mg daily in two or three doses

Special Instructions

Do not drive or perform other potentially dangerous activities until you know whether the medication will impair your ability to do them safely

Take 2 to 3 hours before bed to reduce morning grogginess.

Talk to your doctor before stopping the drug. Your dose may need to be slowly reduced.

Potential Side Effects

Constipation, dry mouth, groggy or drugged feeling, weight gain

Be Aware

Older adults and those with cardiovascular disease should use with caution.

Combining this drug with alcohol or other depressants (including antihistamines, narcotics and some dental anesthetics) can make side effects more severe. 

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.