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Last Updated: 12/30/2024

Tramadol (extended release)

Drug Name(s): Ultram-ER, ConZip-ER

Class: Analgesics

Type: Atypical Opioid

Used for the management of severe and persistent pain that requires an extended treatment period with a daily opioid analgesic and for which alternative treatment options are inadequate.

Dosage

Form(s): extended-release tablet 

The initial is 100 mg once daily. Your doctor may adjust the dose up to 300 mg daily depending on your response to it.

Special Instructions

Do not increase the dose on your own or stop treatment abruptly unless told to do so by a doctor. Do not drive, operate machinery or perform other potentially dangerous activities until you know whether the medication will affect your ability to do them safely. Swallow tablet whole. Do not chew, crush, break open, crush or dissolve.

Potential Side Effects

Constipation; dizziness; drowsiness; dry mouth; headache; increased sweating; itching of skin; nausea; shortness of breath; vomiting; weakness

Be Aware

 Opioids can slow breathing and suppress the cough reflex. Before taking an opioid, tell your doctor if you have a history of lung disease or breathing difficulties. Taking this drug with alcohol or certain other drugs  including benzodiazepines or other central nervous system (CNS) depressants  can increase the risk of dangerous side effects and death. Tell your doctor if you take antihistamines (allergy medications), tranquilizers, sleeping pills, muscle relaxants or other pain medication, or if you have a history of alcohol or drug abuse.

Seizures have been associated with the use of tramadol. Taking this drug with certain antidepressants or with other opioids may increase this risk.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.