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Last Updated: 12/23/2024

Morphine sulphate with naltrexone

Drug Name(s): Generic

Class: Analgesics

Type: Opioid

Used to treat moderate to severe pain when around-the-clock pain relief is needed for an extended period of time.

Dosage

Form(s): extended-release capsule

In a combination pill, 20 to 100 mg morphine and 0.8 to 4 mg naltrexone in a single capsule once or twice a day.

Special Instructions

Must be taken consistently. Not for as-needed relief.

Swallow capsule whole. Do not crush or chew.

Do not increase the dose on your own or stop treatment abruptly unless told to do so by a doctor. Do not drive, operate machinery or perform other potentially dangerous activities until you know whether the medication will affect your ability to do them safely.

Potential Side Effects

Constipation; dizziness; drowsiness; headache; itching; low blood pressure; nausea; vomiting

Be Aware

Opioids can slow breathing and suppress the cough reflex. Before taking an opioid, tell your doctor if you have a history of lung disease or breathing difficulties. Taking opioids with certain other drugs can increase the risk of dangerous side effects. Especially tell your doctor if you take antihistamines (allergy medications), tranquilizers, sleeping pills, muscle relaxants or other pain medication, or if you have a history of alcohol or drug abuse.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.