About Osteoarthritis Clinical Trial Network

The Osteoarthritis Clinical Trial Network is led by world-renowned OA investigators working to create standard protocols for unifying work within the network and the OA scientific community.

Why Osteoarthritis is Important

Osteoarthritis (OA) is the most common form of arthritis and affects 30+ million Americans. OA broadly impacts broadly with a number of contributing factors and co-morbidities.  OA has a significant negative impact on quality of life as well as increased clinical, economic, and social burdens of disease.  OA patients have a tremendous need for effective treatments to improve clinical endpoints (feel/function).  The Arthritis Foundation (AF) must be a leader in OA research to fulfill the needs of its patient constituency.

Osteoarthritis Clinical Trial Network (OA_CTN)

The Arthritis Foundation has taken an approach of focusing on supporting OA clinical research infrastructure.  The platform for clinical trials provided by the Arthritis Foundation serves as a thought leading collaboration for advancement for the overall design and conduct of clinical studies.  This leadership is necessary to change both the scientific and regulatory environment in a way that makes drug developers more likely to study new therapies for osteoarthritis. The OA-CTN is composed of clinical sites led by world-renowned OA investigators with focuses in musculoskeletal MRI, orthopedic surgery, rheumatology, and sports medicine. Members work to generate standard protocols/techniques to unify and accelerate collaborative work within the network and the broader OA scientific community.

Current Focus:

Post-traumatic osteoarthritis (PTOA) is an experimentally important subtype of OA with broad implications for the more prevalent types of OA.

Martin Lotz, MD

Martin Lotz, MD is Head of Arthritis Research and Professor of the Department of Molecular Medicine at the Scripps Research Institute. Dr. Lotz has directed an NIH-funded program on joint aging and osteoarthritis since 1989. Studies on the role of cell death in cartilage led to a project to develop caspase inhibitors for the treatment of post-traumatic arthritis. He is a member of the Arthritis Foundation Board of Directors and the Chair of the Medical and Scientific Advisory Board. 

Jason Kim, PhD

Jason Kim, PhD is the Director of Osteoarthritis Research Program at the Arthritis Foundation. Previously, he spent over 10 years making in vitro diagnostic tests for sickle cell disease, thyroid disorders, cardiac disease, and cancer.  As a corporate scientist and product developer, he has led teams in design control, manufacture transfer, QA/QC, production scale-up, and regulatory approval for the purpose of commercial launch. Trained as a chemist, he received his BSc from the UCLA and his PhD from the UNC Chapel Hill.  He completed his postdoctoral training at the US Naval Research Lab in Washington DC.
Contact Us

Reach out to discuss working on a new or existing clinical trial project. We welcome your questions about the Osteoarthritis Clinical Trial Network (OA-CTN).

I Want to Contribute
I Need Help
  • Donate


    Every gift to the Arthritis Foundation will help people with arthritis across the U.S. live their best life.

  • Volunteer


    Join us and become a Champion of Yes. There are many volunteer opportunities available.

  • Live Yes! INSIGHTS

    Live Yes! INSIGHTS

    Take part to be among those changing lives today and changing the future of arthritis.

  • Partner


    Proud Partners of the Arthritis Foundation make an annual commitment to directly support the Foundation’s mission.


Ways to Give

Every gift to the Arthritis Foundation will help people with arthritis across the U.S. live their best life. Whether it is supporting cutting-edge research, 24/7 access to one-on-one support, resources and tools for daily living, and more, your gift will be life-changing.

Make a Donation

Help millions of people live with less pain and fund groundbreaking research to discover a cure for this devastating disease. Please, make your urgently-needed donation to the Arthritis Foundation now!

Become a Member

Become an Arthritis Foundation member today for just $20 and you'll receive access to helpful tools..... and more. 

Make a Honor or Memorial Gift

Honor a loved one with a meaningful donation to the Arthritis Foundation. We'll send a handwritten card to the honoree or their family notifying them of your thoughtful gift.

Gift Planning

I want information on ways to remember the AF in my will, trust or other financial planning vehicles.


Volunteer Opportunities

The Arthritis Foundation is focused on finding a cure and championing the fight against arthritis with life-changing information, advocacy, science and community. We can only achieve these goals with your help. Strong, outspoken and engaged volunteers will help us conquer arthritis. By getting involved, you become a leader in our organization and help make a difference in the lives of millions. Join us and become a Champion of Yes.

Become a Volunteer

More About Volunteering


Give Just 10 Minutes.

Tell us what matters most to you. Change the future of arthritis.

By taking part in the Live Yes! INSIGHTS assessment, you’ll be among those changing lives today and changing the future of arthritis, for yourself and for 54 million others. And all it takes is just 10 minutes.

Your shared experiences will help:

- Lead to more effective treatments and outcomes
- Develop programs to meet the needs of you and your community
- Shape a powerful agenda that fights for you

Now is the time to make your voice count, for yourself and the entire arthritis community. 

Currently this program is for the adult arthritis community.  Since the needs of the juvenile arthritis (JA) community are unique, we are currently working with experts to develop a customized experience for JA families. 

How are you changing the future?

By sharing your experience, you’re showing decision-makers the realities of living with arthritis, paving the way for change. You’re helping break down barriers to care, inform research and create resources that make a difference in people’s lives, including your own.

Get Started


Meet Our Partners

As a partner, you will help the Arthritis Foundation provide life-changing resources, science, advocacy and community connections for people with arthritis, the nations leading cause of disability. Join us today and help lead the way as a Champion of Yes.


Our Trailblazers are committed partners ready to lead the way, take action and fight for everyday victories. They contribute $2,000,000 to $2,749,000


Our Visionary partners help us plan for a future that includes a cure for arthritis. These inspired and inventive champions have contributed $1,500,00 to $1,999,999.


Our Pioneers are always ready to explore and find new weapons in the fight against arthritis. They contribute $1,000,000 to $1,499,999.


Our Pacesetters ensure that we can chart the course for a cure for those who live with arthritis. They contribute $500,000 to $999,000.


Our Signature partners make their mark by helping us identify new and meaningful resources for people with arthritis. They contribute $250,000 to $499,999.


Our Supporting partners are active champions who provide encouragement and assistance to the arthritis community. They contribute $100,000 to $249,999.