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Last Updated: 1/7/2025

Mycophenolic acid

Drug Name(s): CellCept, Myfortic

Class: Immunosuppresants

Used to treat lupus nephritis (off-label).

Dosage

Form(s): capsule, delayed-release tablet

1000 mg twice daily to start.  Dosage may be adjusted to 500 mgs to 3000 mgs per day.

Special Instructions

Do not crush, chew, or cut capsules or delayed-release tablets.

Take with a corticosteroid as directed by your doctor.

Potential Side Effects

Changes in laboratory blood levels including high levels of blood sugar; constipation; diarrhea; dizziness; fast heartbeat; headache; infections; low white and red blood cell counts; nausea and vomiting; swelling of the lower legs, ankles and feet, rash

Be Aware

Use during pregnancy is associated with increased risks of pregnancy loss and birth defects. Women of childbearing potential should use effective birth control and/or consider different treatment options.  This drug is associated with increased risk of malignancies including lymphoma and skin cancers.  Using this drug increases risk of infection, including opportunistic infection. 

This drug is associated with blood disorders. Your doctor will monitor your blood while you take this medication  to infection 

Let your doctor know if you have active digestive system disease. This drug is associated with serious GI tract complication, including GI bleeding, perforations and ulcers. 

This drug may cause exacerbation of Hereditary Deficiency of Hypoxanthine-guanine Phosphoribosyl-transferase (HGPRT), an inborn error of purine metabolism associated with uric acid overproduction and neurological manifestations.

Avoid live attenuated vaccines while using this medication.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.