Last Updated: 12/23/2024
Apremilast
Drug Name(s): Otezla
Class: DMARDs
Dosage
Form(s): tablet
Starting dose is 10 mg daily, increased over five days to a maintenance dose of 30 mg twice a day. A lower dosage of 30 mg once a day is recommended for patients with severe kidney disease
Potential Side Effects
Diarrhea; headache; nausea; weight loss
Be Aware
Do not take with strong cytochrome P450 enzyme inducers, such as carbamazepine, rifampin, phenobarbital or phenytoin.
You should monitor your weight regularly when taking this drug. Tell your doctor if you have unexplained or clinically significant weight loss.
This drug may cause depression or worsening of depression. Tell your doctor immediately if you have new or worsening depression, suicidal thoughts or other mood changes.
The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.
