Apremilast
Drug Name(s): Otezla
Class: DMARDs
Dosage
Form(s): tablet
Starting dose is 10 mg daily, increased over five days to a maintenance dose of 30 mg twice a day. A lower dosage of 30 mg once a day is recommended for patients with severe kidney disease
Special Instructions
You should monitor your weight regularly when taking this drug. Tell your doctor if you have unexplained or clinically significant weight loss.
Potential Side Effects
Diarrhea; headache; nausea; weight loss
Be Aware
Do not take with strong cytochrome P450 enzyme inducers, such as carbamazepine, rifampin, phenobarbital or phenytoin.
This drug may cause depression or worsening of depression. Tell your doctor immediately if you have new or worsening depression, suicidal thoughts or other mood changes.
Severe allergic reactions may occur with this drug. Call your doctor or get emergency help if you have trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.
