Drug Class: Biologics (IL-inhibitor)
  Brand Names: Stelara


Injection: For adults under 100 kg (220 lbs): 45 mg initially and 4 weeks later, followed by 45 mg every 12 weeks. For adults over 100 kg: 90 mg initially and 4 weeks later, followed by 90 mg every 12 weeks.

Potential Side Effects

Back pain; diarrhea; fatigue; headache; upper respiratory infection.

Special Instructions

Women of childbearing age should use effective contraception during treatment.


Be Aware

All biologics suppress the immune system and may increase your risk of infections. Tell your doctor if you have an active infection. Do not start treatment if you have a serious or recurrent infection (such as pneumonia). You should be tested for tuberculosis before starting this medication. Do not get a live vaccine when taking biologics.

Multiple squamous cell skin cancers have been reported in patients receiving ustekinumab who had pre-existing risk factors for non-melanoma skin cancer. Your doctor should examine your skin for changes while you are taking this drug.

LAST UPDATED: 03/28/2014

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.