Last Updated: 7/14/2025
Lifitegrast
Drug Name(s): Xiidra
Class: Immunosuppresants
Used to treat eye dryness associated with Sjögren’s syndrome.
Dosage
Form(s): single-use vial
One drop twice daily in each eye, approximately 12 hours apart
Special Instructions
If you wear contact lenses, remove them before applying lifitegrast and wait for at least 15 minutes before placing them back in your eyes. Use solution from one single-use container immediately after opening. It can be used to dose both eyes. The single-use container, including any remaining contents should be discarded immediately after administration.
Potential Side Effects
Eye irritation; discomfort or blurred vision when the drops are applied to the eyes; unusual taste sensation
Be Aware
You will need regular eye exams while you are on this treatment.
The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.
