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ES
Last Updated: 7/15/2025

Ibandronate

Drug Name(s): Boniva

Class: Bisphosphonates

Used in the treatment and prevention of postmenopausal osteoporosis.

Dosage

Form(s): tablet, prefilled syringe

150 mg in a single monthly dose or 3 mg IV every three months

Special Instructions

Swallow whole with liquid. Do not split, crush, chew or dissolve tablets. Take at least 30 minutes before meals.

Remain upright (sitting or standing) for at least 30 to 60 minutes after ingesting.

Do not eat or drink anything else or take any other medication, including calcium tablets, for at least 60 minutes.

Take supplemental calcium and vitamin D if dietary intake inadequate.

IV form is administered by a professional.

Potential Side Effects

Heartburn; stomach pain; joint pain and fever may accompany infusions, most commonly with first infusion

Be Aware

Before taking this medication, tell your doctor if you are taking aspirin or aspirin-containing products.

Blood levels of calcium and vitamin D must be normal before starting therapy. If they are low, your doctor may recommend supplementation with ergocalciferol or cholecalciferol before taking potent bisphosphonates. Rarely, osteonecrosis of the jaw has been reported in patients treated with bisphosphonates. You should have dental checkup before starting bisphosphonates. Bisphosphonates have also been linked to a rare type of leg fracture. Tell your doctor if you have persistent leg pain.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.