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Last Updated: 12/20/2024

Betamethasone

Drug Name(s): Celestone Soluspan, Diprolene, Sernivo, generic

Class: Corticosteroids

Used to control inflammation in inflammatory skin conditions, gout, ankylosing spondylitis (AS), rheumatoid arthritis (RA), lupus and other inflammatory forms of arthritis.

Dosage

Form(s): injection, tablet, topical cream, spray 

Dosages of corticosteroids vary widely, depending on which disease is being treated.

Special Instructions

Take oral corticosteroids with food. A single daily dose should be taken with breakfast. Sometimes the dose is split and taken several times a day.

Potential Side Effects

Bruising; cataracts; heart problems, including heart attack and stroke; high blood pressure, high cholesterol and high triglycerides; increased blood sugar; glaucoma; hardening of arteries (atherosclerosis); increased appetite; increased risk of infection, indigestion; insomnia; mood swings; muscle weakness; nervousness or restlessness; osteoporosis; stomach ulcers; thin skin; weight gain

Be Aware

Corticosteroids may have a greater effect in people who have had liver scarring (cirrhosis) or underactive thyroid (hypothyroidism); therefore, a smaller dosage may be recommended. During periods of unusual stress, your dosage may need to be increased.

Taking corticosteroids make you more likely to get an infection; the drugs also can mask the signs of an infection. Before starting corticosteroids, tell your doctor if you have an active infection or history of tuberculosis. Also tell your doctor if you think you’ve come in contact with someone who is sick with a serious infection such as chickenpox or measles. Corticosteroids may reduce the body’s response to vaccines.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.