Drug Class: Biologics (IL-inhibitor)
  Brand Names:  Taltz


For psoriatic arthritis: after an initial loading dose of 160 mg, 80 mg injection every 4 weeks. 

For psoriatic arthritis in the presence of coexistent moderate-to-severe plaque psoriasis: after an initial loading dose of 160 mg, 80 mg injection every 2 weeks for the first 12 weeks, and every 4 weeks thereafter.

For ankylosing spondylitis: after an initial loading dose of 160 mg, 80 mg injection every 4 weeks.

For non-radiographic axial spondylitis: 80 mg every 4 weeks.

Potential Side Effects

Caution should be used when prescribing ixekizumab to patients with inflammatory bowel disease. Exacerbations, in some cases serious, occurred in ixekizumab-treated patients during clinical trials.

Special Instructions

Must be kept refrigerated. Do not freeze. Inject into thigh, abdomen or upper arm. Rotate injection sites. Do not inject where skin is tender, bruised, red or hard.

Be Aware

All biologics suppress the immune system and may increase your risk of infections. Tell your doctor if you have an active infection. Do not start treatment if you have a serious or recurrent infection (such as pneumonia). You should be tested for tuberculosis before starting this medication. Do not get a live vaccine when taking biologics.

LAST UPDATED: 6/3/2020

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.