Guselkumab
Drug Name(s): Tremfya
Class: Biologics
Type: IL-Inhibitor, IL-23
Used in the treatment of psoriatic arthritis (PsA) in adults and in children aged 6 and older who weigh at least 40 kg.
Dosage
Form(s): prefilled syringe
100 mg administered by subcutaneous injection at week 0, week 4 and every 8 weeks thereafter.
Special Instructions
Keep refrigerated but do not freeze. Do not shake the filled syringe. Before injection, allow guselkumab to reach room temperature without removing the needle cap. Can be used alone or in combination with a conventional disease-modifying antirheumatic drug (DMARD) such as methotrexate.
Potential Side Effects
Infection (fever, chills, wounds that don't heal); headache, pain, injection site redness or swelling, joint pain, and stomach problems (diarrhea, abdominal pain). It’s possible to have a severe allergic reaction after first dose (skin rash, nausea, vomiting, difficulty breathing).
Be Aware
This and all biologics suppress the immune system and may increase your risk of infections. Tell your doctor if you have an active infection. Do not start treatment if you have a serious or recurrent infection (such as pneumonia). You should be tested for tuberculosis before starting this medication. Do not get a live vaccine when taking biologics.
