Risedronate sodium
Drug Name(s): Actonel, Atelvia, generic
Class: Bisphosphonates
Used for the treatment and prevention of postmenopausal osteoporosis, treatment to increase bone mass in men with osteoporosis, treatment and prevention of glucocorticoid-induced osteoporosis.
Dosage
Form(s): regular or extended-release tablet
Actonel:
- For corticosteroid-induced osteoporosis: 5 mg once daily
- For treatment and prevention of osteoporosis for men or women: 5 mg once daily or 35 mg once weekly
- For treatment in women: two doses of 75 mg each on two consecutive days or 150 mg once a month
Atelvia: For postmenopausal women: 35 mg once weekly.
Special Instructions
Swallow whole; do not split, crush, chew or dissolve tablets. Take with a full glass of water first thing in the morning.
Remain upright (sitting or standing) at least 30 to 60 minutes after ingesting.
Do not eat or drink anything else or take any other medication or supplements for at least 60 minutes.
Potential Side Effects
Heartburn; stomach pain
Be Aware
Before taking this medication, tell your doctor if you are taking aspirin or aspirin-containing products.
Blood levels of calcium and vitamin D must be normal before starting therapy. If they are low, your doctor may recommend supplementation with ergocalciferol or cholecalciferol before taking potent bisphosphonates.
Rarely, osteonecrosis of the jaw has been reported in patients treated with bisphosphonates. You should have dental checkup before starting bisphosphonates. Bisphosphonates have also been linked to a rare type of leg fracture. Tell your doctor if you have persistent leg pain.
