Alendronate
Drug Name(s): Binosto, Fosamax
Class: Bisphosphonates
Used to prevent or treat osteoporosis in postmenopausal women, to increase bone mass in men with osteoporosis, and to treat osteoporosis in men or women taking corticosteroids.
Dosage
Form(s): tablet
- For corticosteroid-induced osteoporosis: 5 mg once a day for men and postmeno-pausal women receiving estrogen; 10 mg once a day for postmenopausal women not receiving estrogen.
- For osteoporosis in men and postmenopausal women: 70 mg once weekly or 10 mg once a day
- For osteoporosis prevention: 5 mg once a day or 35 mg once a week
Special Instructions
Swallow whole; do not split, crush, chew or dissolve tablets. Take with a full glass of water first thing in the morning.
Remain upright (sitting or standing) at least 30 to 60 minutes after ingesting.
Do not eat or drink anything else or take any other medication or supplements for at least 60 minutes.
Potential Side Effects
Bone, muscle or joint pain; heartburn; stomach pain
Be Aware
Blood levels of calcium and vitamin D must be normal before starting therapy. If they are low, your doctor may recommend supplementation with ergocalciferol (vitamin D2) or cholecalciferol (vitamin D3) before taking potent bisphosphonates. Rarely, osteonecrosis (bone death) of the jaw has been reported in patients treated with bisphosphonates. You should have a dental checkup before starting bisphosphonates. Bisphosphonates have also been linked to a rare type of leg fracture. Tell your doctor if you have persistent leg pain.
