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Last Updated: 8/29/2025

Mycophenolate mofetil

Drug Name(s): CellCept

Class: DMARDs

Type: Immunosuppressant

This immunosuppressant medication is FDA-approved to prevent organ transplant rejection. It is used off-label to treat several rheumatic diseases, including lupus nephritis and systemic sclerosis (scleroderma) as well as uveitis.

Dosage

Form(s): tablet or capsule

1 to 1.5 grams twice daily; varies by disease

Special Instructions

Do not take if pregnant, breastfeeding or if you may become pregnant. Men must use a condom. Increased risk of serious infection.

Potential Side Effects

Constipation; diarrhea; dizziness; fast heartbeat; headache; low white and red blood cell counts; nausea and vomiting; swelling of the lower legs, ankles, feet, hands and arms.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.