Naproxen and esomeprazole magnesium
Drug Name(s): Vimovo, generic
Class: NSAIDs
Type: Combined with a proton pump inhibitor (PPI)
Used in the treatment of osteoarthritis (OA), rheumatoid arthritis (RA), and ankylosing spondylitis (AS).
Dosage
Form(s): extended-release tablet
One tablet (containing 375 mg naproxen and 20 mg esomeprazole or 500 mg naproxen and 20 mg esomeprazole) twice a day.
Special Instructions
Do not take with other prescription or over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs).
Take at the same time every day.
Swallow whole. Do not cut, chew, crush, divide or dissolve.
Take at least 30 minutes before a meal.
Potential Side Effects
Abdominal cramps, pain or discomfort; diarrhea; dizziness; drowsiness; gastrointestinal bleeding; headache; heartburn; high blood pressure; nausea or vomiting; peptic ulcer; swelling of feet; rash; ringing in the ears
Be Aware
- Using ibuprofen or naproxen with low-dose aspirin may interfere with aspirin’s ability to help prevent heart attacks.
- Before taking any type of NSAID, tell your doctor if you drink alcohol or take blood thinners (including warfarin), ACE inhibitors, lithium or furosemide. Also report any sensitivity or allergy to aspirin or similar drugs.
- All non-aspirin NSAIDs may cause an increased risk of serious blood clots, heart attack and stroke, which can be fatal. This risk increases with dose and duration of use. Patients who have or who are at risk for cardiovascular disease are at greater risk for these complications.
- NSAIDs increase the risk of serious gastroinestinal side effects, including bleeding, ulceration, and gastric or intestinal perforation, which can be fatal.
- Do not take NSAIDs late in pregnancy.
