Drug Class: DMARDs
Brand Names: Xeljanz, Xeljanz XR
Xeljanz: 5 mg twice daily; 5 mg once daily for patients with reduced kidney or liver function.
Xeljanz XR: 11 mg once daily.
Potential Side Effects
Decrease in blood counts; diarrhea; headache; hypertension; increased lipid levls; upper respiratory tract infection. Boxed warning for the risk of serious infections, malignancies.
May be taken with or without food.
Do not chew tablets; do not crush enteric-coated or time-release pills or mix with water.
Your doctor should order periodic blood and urine tests to check for unwanted effects. Before taking any DMARD, tell your doctor if you are planning to become pregnant.
Tofacitinib suppresses the immune system and may increase the risk of infections and certain cancers. Your doctor will test you for tuberculosis (TB) before starting this drug. Tell your doctor if you have a history of TB. Live vaccines should not be given with tofacitinib.
LAST UPDATED: 06/05/2018