Methotrexate
Drug Name(s): Trexall, Xatmep, Otrexup, Rasuvo, generic
Class: DMARDs
Used to treat rheumatoid arthritis (RA), dermatomyolsitis, and polyarticular JIA.
Dosage
Form(s): tablet, oral solution, injection
7.5 to 30 mg in a single weekly dose.
Dosages for children: The dosages listed above are those typically prescribed for adults aged 18-65. Dosages for children can vary. Ask your doctor about the appropriate dosage for your child.
Special Instructions
Avoid aspirin and other salicylates.
Drink plenty of fluids while taking this medication.
Your doctor may prescribe folic acid to reduce side effects, including mouth sores.
Minimize exposure to sunlight and wear sunscreen.
Potential Side Effects
Abdominal discomfort; chills; dizziness; fever; general feeling of illness; hair loss; headache; increased sun sensitivity; itching; liver problems; low blood counts; mouth sores; nausea; rash; shortness of breath; yeast infections
Be Aware
Your doctor should order periodic blood and urine tests to check for unwanted effects. Before taking any DMARD, tell your doctor if you are planning to become pregnant.
Discuss any alcohol use with your doctor.
Tell your doctor immediately if you have a dry cough, fever or difficulty breathing, as these symptoms may be associated with serious medication side effects.
