Emapalumab-lzsg
Drug Name(s): Gamifant
Class: DMARDs
This medication is used to treat adults and children with macrophage activation syndrome in known or suspected cases of Still’s disease (including sJIA) that don’t respond adequately to corticosteroids.
Uses
macrophage activation syndrome (MAS) in Still’s disease, including systemic Juvenile Idiopathic Arthritis (sJIA), with inadequate response or intolerance to corticosteroids
Dosage
Form(s): injection, infusion
Infusion: 6 mg/kg initial dose, followed by 3 mg/kg every 3 days for 5 doses, then 3 mg/kg up to 10mg/kg twice per week
Injection: 5mg/mL up to 25mg/mL
Special Instructions
Your doctor will evaluate your risk of tuberculosis and may give you medication to prevent herpes zoster or other infections before starting this drug.
Tell your doctor if you develop any signs of infection after receiving it.
Gamifant is given by injection or infusion in a doctor’s office or other clinical facility.
Potential Side Effects
Fever, rash, tingling feeling, headache
Be Aware
This drug raises your risk of developing infections, including herpes zoster, pneumonia or other bacterial, viral or fungal infections.
Talk to your doctor before getting any live vaccines.
Talk to your doctor if you are or may become pregnant or breast-feeding while taking this drug.
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