Arthritis Foundation-Supported Study Leads to Osteoarthritis Breakthrough

Results from $3.4 million study could improve diagnosis and treatment for one of the most prevalent and disabling diseases in the world

ATLANTA, November 16, 2015 – The Foundation for the National Institutes of Health (FNIH) recently announced results from a study that determined which biomarkers have the greatest ability to measure early progression of osteoarthritis (OA) of the knee. The study was supported by the FNIH Biomarkers Consortium with scientific and financial contributions from public and private sector entities including the Arthritis Foundation.

The study’s findings are particularly impactful for the more than 27 million Americans living with OA, as the newly identified biomarkers will better predict treatment response and could lead to improved individualized treatment and care.

“Currently, osteoarthritis treatments focus solely on symptoms versus the joint disease itself and the resulting structural changes,” explained Arthritis Foundation national scientific director, Amanda Niskar. “The new biomarkers will allow for a focus on both aspects, not only leading to improved care, but better identification of new treatment targets and ultimately more efficient drug trials.”

The study used data from nearly 5,000 OA knee patients and controls and was led by David J. Hunter, M.D., Ph.D., from the University of Sydney in Australia and Arthritis Foundation national board member, Virginia Byers Kraus, M.D., Ph.D., from Duke University.

“The Arthritis Foundation’s new scientific strategy is designed to take a more nimble approach to accelerating science that will improve the lives of people living with arthritis,” said Niskar. “There’s a need for new osteoarthritis treatments and the results of this study could go a long way in addressing this. Our goal is for this study to be one of many on our path to a cure for arthritis.”

For more information on the FNIH Biomarkers Consortium Study, you can visit:, or if you’d like to learn more about the Arthritis Foundation’s scientific strategy and path to a cure, please visit:

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