Workshop 1

LUPUS: PROGRESS IN UNDERSTANDING MECHANISMS
AND ASSESSING ACTIVITY (pdf)
Moderator: Philip Cohen, MD, University of Pennsylvania

Topics:

• EPISTATIC EFFECTS OF THE SLE1C LUPUS SUSCEPTIBILITY INTERVAL ON NZB AUTOIMMUNE PHENOTYPES
  Susan Boackle, MD, University of Colorado Health Sciences Center
  
  
• GENE PREDICTORS OF DISEASE ACTIVITY IN
  SYSTEMIC LUPUS ERYTHEMATOSUS
  Emily Baechler, PhD, University of Minnesota
  
  
• AUTOIMMUNE LUPUS TRIGGERED BY MINOR
  ALLOANTIGENS IN ALLOGENEIC HOSTS
  Chunyan Zhang, MD, PhD, Beckman Research Institute of City of Hope
  
  
• TOLL-LIKE RECEPTOR AGONISTS STIMULATE
  AUTOREACTIVE B CELLS
  Jun Yan, MD, PhD, University of Louisville
  
  
• MODULATION OF MURINE LUPUS BY AN INHIBITORY GPG OLIGONUCLEOTIDE
  Lowen Lee, Stanford University
  
  
• INTERFERON INDUCIBLE PROTEINS ARE NOVEL AUTOANTIGENS IN SYSTEMIC LUPUS ERYTHEMATOSUS
  Donna Thibault, Stanford University
  
  
• RETICULOCYTES BEARING COMPLEMENT C4D MAY SERVE AS "INSTANT MESSENGERS" OF DISEASE ACTIVITY IN SLE
  Joseph Ahearn, MD, University of Pittsburgh

Workshop 2

CLINICAL OUTCOMES AND EPIDEMIOLOGY
OF RHEUMATIC DISEASES (pdf)
Moderator: Susan Manzi, MD, MPH, University of Pittsburgh

Topics:

• PREDICTORS OF PARENTAL PERCEPTIONS
  OF CHILD VULNERABILITY IN PARENTS OF YOUNG
  CHILDREN WITH ARTHRITIS
  Kelly Anthony, PhD, Duke University Medical Center
  
  
• RHEUMATOID FACTOR SEROPOSITIVITY IN A NORMAL POPULATION IS ASSOCIATED WITH THE USE OF ORAL CONTRACEPTIVES AND CIGARETTE SMOKING
  Kevin Deane, MD, University of Colorado Health Sciences Center
  
  
• COMPLEMENT C4-DERIVED LIGANDS ON PLATELETS AS BIOMARKER FOR PROGRESSION OF CAROTID INTIMA-MEDIA THICKNESS IN WOMEN WITH SYSTEMIC LUPUS
  Amy Kao, MD, MPH, University of Pittsburgh
  
  
• IMBALANCE OF ENDOTHELIUM DAMAGE/REGENERATION IN SYSTEMIC LUPUS ERYTHEMATOSUS
  Mariana Kaplan, MD, University of Michigan Medical School
  
  
• ASSOCIATION OF VITAMIN K WITH HAND OSTEOPHYTES
  Tuhina Neogi, MD, FRCPC, Boston University School of Medicine
  
  
• USE OF BLOOD GENE EXPRESSION PROFILING TO UNDERSTAND SLE PATHOGENESIS AND MONITOR DISEASE ACTIVITY
  Virginia Pascual, MD, Baylor Institute for Immunology Research
  
  
• CARDIOVASCULAR RISK PROFILES OF PATIENTS
  WITH RA IN THE BRASS COHORT
  Daniel Solomon, MD, MPH, Brigham & Women’s Hospital

Workshop 3

EMERGING TECHNOLOGIES FOR STUDYING
RHEUMATIC DISEASES (pdf)
Moderator: P.J. Utz, MD, Stanford University

Topics:

• PLASMA LEVELS OF COMPLEMENT PROTEINS AND MAC BOUND TO CIRCULATING IMMUNE COMPLEXES (CIC) IN RA AND SLE
  Anil Chauhan, PhD, ProGen Biologics
  
  
• RADIOGRAPHIC COMPARISON OF KNEE JOINT ARTICULAR CARTILAGE AND SUBCHONDRAL BONE OF OSTEOGENESIS IMPERFECTA AND WILD TYPE MICE USING MICRO-CT
  AND MICRO-MR
  Niccolo Fiorentino, BS, National Institutes of Health
  
  
• PROTEOMIC ANALYSIS OF SECRETED PROTEINS DEFINES SUBTYPES OF RHEUMATOID ARTHRITIS
  Wolfgang Hueber, MD, Stanford University
  
  
• PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS
  BY COMPLEMENT RECEPTOR CR2/CR1 DEFICIENCY
  Kristine Kuhn, University of Colorado Health Science Center
  
• MOLECULAR PORTRAITS OF SCLERODERMA
  Ausra Milano, PhD, Dartmouth Medical School
  
  
• DEVELOPMENT OF MASS SPECTROMETRY AND PROTEIN
  ARRAY TECHNOLOGIES TO IDENTIFY BIOSIGNATURES
  IN RHEUMATOID ARTHRITIS
  William Robinson, MD, PhD, Stanford University School of Medicine
  
  
• AUTOANTIGEN MICROARRAYS TO SURVEY
  IMMUNOLOGIC RESPONSIVENESS
  Gregg Silverman, MD, University of California at San Diego

Workshop 4

B CELL TOLERANCE (pdf)
Moderator: Gregg Silverman, MD, University of California at San Diego

Topics:

• EFFECT OF DEPLETION OF B CELLS ON MURINE LUPUS
  Anupama Ahuja, PhD, Yale University
  
  
• IMMUNOLOGIC EFFECTS OF B CELL DEPLETION
  WITH RITUXIMAB IN HUMAN SLE
  Jennifer Anolik, MD, PhD, University of Rochester Medical Center
  
  
• MATURE SPLENIC B-CELL SUBSETS ARE DISCORDANT IN THEIR DEPENDENCE ON BIM FOR IN VIVO BCR-MEDIATED CELL DEATH
  Carl Goodyear, PhD, University of California at San Diego
  
  
• RECEPTOR EDITING: CAUSES AND CONSEQUENCES
  Nina Luning Prak, MD, PhD, University of Pennsylvania
  
  
• SELECTIVE THERAPEUTIC BLOCKADE OF HUMAN FCRN IN TREATMENT OF HUMORALLYMEDIATED AUTOIMMUNE DISEASE
  Derry Roopenian, PhD, Jackson Laboratory
  
  
• DEFECTIVE B CELL TOLERANCE CHECKPOINTS IN PATIENTS
  WITH SYSTEMIC LUPUS ERYTHEMATOSUS
  Sergey Yurasov, MD, PhD, Rockefeller University, Memorial Sloan-Kettering
  Cancer Center

Workshop 5

REGULATION OF EXTRACELLULAR MATRIX
AND INFLAMMATION IN PHYSIOLOGICAL AND
PATHOLOGICAL PROCESSES (pdf)
Moderator: John Varga, MD, Northwestern University

Topics:

• TGF-β SIGNALING REGULATES MECHANICAL PROPERTIES AND COMPOSITION OF BONE MATRIX
  Tamara Alliston, PhD, University of California, San Francisco
  
  
• INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN
  INDUCES LUNG FIBROSIS: A NOVEL MURINE MODEL
  OF PULMONARY FIBROSIS
  Carol Feghali-Bostwick, PhD, University of Pittsburgh
  
  
• IDENTIFICATION OF A TNFα RESPONSIVE GENE THAT
  INHIBITS BMP SIGNAL TRANSDUCTION
  Olexandr Korchynskyi, PhD, University of North Carolina at Chapel Hill
  
  
• BROADLY EXPRESSED GENES ACCOUNT FOR THE SPATIAL RESTRICTION OF ECM MINERALIZATION TO BONE
  Monzur Murshed, PhD, Baylor College of Medicine
  
  
• THE ROLE OF TGF-BETA AND IL6 IN POST-INJURY SYNOVIAL LINING RESTITUTION
  Anna Plaas, PhD, University of South Florida
  
  
• SERUM AMYLOID A INDUCED INFLAMMATORY ACTIVITIES ARE INHIBITED BY UTEROGLOBIN VIA THE LIPOXIN A4 RECEPTOR ALX IN HL-60 AND FIBROBLAST-LIKE SYNOVIOCYTES
  Snezna Sodin-Semrl, MS, PhD, University of Illinois at Chicago

Workshop 6

PATHOGENESIS OF HUMAN RA AND ITS
MURINE MODELS (pdf)
Moderator: Michael Holers, MD, University of Colorado Health Science Center


Topics:

• FIBRINOGEN-INDUCED ARTHRITIS IN MICE AS A NOVEL
  MODEL FOR RHEUMATOID ARTHRITIS
  Peggy Ho, PhD, Stanford University School of Medicine
  
  
• ANTIBODIES TO CITRULLINE-MODIFIED PROTEINS ENHANCE TISSUE INJURY IN INFLAMMATORY ARTHRITIS
  Kristine Kuhn, University of Colorado Health Sciences
  
  
• MAST CELL IL-1 PLAYS A CRITICAL ROLE IN K/BXN SERUM TRANSFER ARTHRITIS AND MAY RESULT FROM
  ACTIVATION VIA FcγRIII
  Peter Nigrovic, MD, Brigham & Women’s Hospital/Harvard Medical School
  
  
• IMPAIRED EARLY B CELL TOLERANCE IN PATIENTS
  WITH RHEUMATOID ARTHRITIS
  Jonathan Samuels, MD, Hospital for Special Surgery/Cornell
  
  
• DENDRITIC CELLS OVEREXPRESSING IL-4 EXHIBIT ENHANCED PRODUCTION OF PROINFLAMMATORY CYTOKINES AND AMELIORATE ARTHRITIS
  Sujata Sarkar, MD, University of Michigan
  
  
• DRB1 *401 RENDERS ONLY FEMALE MICE SUSCEPTIBLE TO COLLAGEN-INDUCED ARTHRITIS
  Veena Taneja, PhD, Mayo Clinic
  
  
• TRANSCRIPTION FACTOR T-BET REGULATES INFLAMMATORY ARTHRITIS THROUGH ITS FUNCTION IN DENDRITIC CELLS
  Jingsong Wang, MD, Brigham & Women’s Hospital/Harvard Medical School

Workshop 7

SLE: APOPTOSIS AND INTERFERONS (pdf)
Moderator: Antony Rosen, MD, Johns Hopkins University


Topics:

• AUTOANTIGEN-DEPENDENT PHAGOCYTOSIS BY DENDRITIC CELLS: A PATHOGENIC ROLE FOR OPSONIZED APOPTOTIC
  BLEBS IN SYSTEMIC LUPUS ERYTHEMATOSUS
  Roberto Caricchio, MD, University of Pennsylvania
  
  
• REGULATION OF ANTI-DNA ANTIBODIES BY APOPTOSIS
  Deep Charan, University of Pennsylvania
  
  
• INF-α ROLE IN TOLERANCE MAINTENANCE
  Jin-Young Choi, PhD, Yale School of Medicine
  
  
• UPREGULATION OF THE 9-2 ISOFORM OF THE 2'-5' OLIGOADENYLATE SYNTHETASE (OAS) 1 GENE SUGGESTS A NOVEL APOPTOTOIC PATHWAY IN CUTANEOUS LUPUS
  Selwyn Chow, MD, Weill Medical College of Cornell University
  
  
• THE ROLE OF LYMPHOID NEOGENESIS IN THE PATHOGENESIS
  OF EXPERIMENTAL LUPUS
  Dina Nacionales, MD, University of Florida
  
  
• THE DIVERGENT ROLE OF INTERFERON REGULATORY
  FACTOR-1 IN LUPUS MICE
  Christopher Reilly, PhD, Virginia Polytechnic Institute
  
  
• NITROTYROSINE-MODIFIED PROTEINS AS TARGET AUTOANTIGENS FOR LUPUS NEPHRITIS IN BXD2 MICE
  Hui-Chen Hsu, PhD, University of Alabama at Birmingham

Workshop 8

BIOLOGY OF ARTICULAR CARTILAGE AND TISSUE ENGINEERING STRATEGIES FOR ITS REPAIR (pdf)
Moderator: Zvi Schwartz, DMD, PhD, Hebrew University/Georgia
Institute of Technology


Topics:

• TISSUE ENGINEERING FOR RHEUMATOID ARTHRITIS
  Julia Babensee, PhD, Georgia Institute of Technology
  
  
• HYDROGELS IN CARTILAGE REPAIR
  Jennifer Elisseeff, PhD, Johns Hopkins University
  
  
• EXPRESSION OF PRE-ADIPOCYTE FACTOR-1 IN ARTICULAR CARTILAGE AND CHONDROCYTES
  Chisa Hidaka, MD, Hospital for Special Surgery
  
  
• ROLE OF WISP3 IN MAINTENANCE OF CARTILAGE INTEGRITY
  Malini Sen, PhD, University of California at San Diego
  
  
• THE TRANSCRIPTION FACTORS L-SOX5 AND SOX6 CONTROL CHONDROCYTE DIFFERENTIAL, PROLIFERATION AND EXTRACELLULAR MATRIX
  Patrick Smits, PhD, Cleveland Clinic Foundation
  
  
• CONDITIONAL DELETION OF THE TGB-β TYPE II RECEPTOR IN PRX-1 EXPRESSING CELLS RESULTS IN DEFECTS IN THE AXIAL SKELETON INCLUDING JOINT FORMATION AND CALVARIA AGENESIS
  Anna Spagnoli, MD, Vanderbilt University School of Medicine
  
  
• SELECTIVE AND NON-SELECTIVE PROTEASE INHIBITORS REDUCE IL-1 INDUCED DEGRADATION AND LOSS OF MECHANICAL PROPERTIES IN ARTICULAR CARTILAGE
  Christopher Wilson, MS, Georgia Institute of Technology