Lee C. Howley Sr. Prize for Arthritis Research

The Lee C. Howley Sr. Prize for Research in Arthritis recognizes those researchers whose contributions during the previous five years have represented a significant advance in the understanding, treatment or prevention of arthritis and rheumatic diseases. It is a fitting memorial tribute to Lee C. Howley Sr., former chairman of Revco D.S., Inc., who was instrumental in the establishment of the Revco Arthritis Research Center at Case Western Reserve University in Cleveland, Ohio.

The Arthritis Foundation extends its gratitude to the Howley family on behalf of the estimated 50 million Americans who have arthritis for making the Lee C. Howley Sr. Prize for Research in Arthritis possible. The recognition that this program offers for excellence in arthritis research will ensure that the search will continue for cures to the more than 100 forms of arthritis and the rheumatic diseases. The Howley family's expression of commitment offers hope that one day the problems of arthritis will be solved.

The recipients of the 2011 Lee C. Howley Sr. Prize for Arthritis Research are Alisa Erika Koch, MD Professor of Rheumatology at the University of Michigan and Andrew D. Luster, MD, PhD Chief of Rheumatology, Allergy & Immunology and Director of the Research Center for Immunology & Inflammatory Diseases at Massachusetts General Hospital.

Dr. Koch studied extensively at Northwestern and Loyola, concentrating on immunopatheogenesis, cell adhesion, angiogenesis and cytokines, as they relate to the treatment of rheumatoid arthritis (RA). Through her lab work and many contributions to prestigious scientific journals, Dr. Koch has made a major impact on RA treatments.

Through his work at Duke, Rockefeller, Cornell and Harvard, Dr. Luster has been a pioneer in the birth, growth and development of the chemokine field. His laboratory at Massachusetts General Hospital has helped define how chemokines function in immune cell trafficking and in the patheogenesis of immune and inflammatory diseases like arthritis.

Previous recipients include Wayne M. Yokoyama, MD, John O’Shea, MD, Gerard Karsenty, MD, PhD, Michel Nussenzweig, MD, PhD, Gary Koretzky, MD, David Wofsy, MD, Gary Firestein, MD, Chella David, PhD, David Felson, MD, MPH, Jeffrey Ravetch, MD, David V. Goeddel, PhD, Betty Diamond, MD, Peter Lipsky, MD, David S. Pisetsky, MD, PhD, Daniel Kastner, MD, PhD, Morris Reichlin, MD, Matthew H. Liang, MD, MPH, William P. Arend, MD, Arthur Weiss, MD, PhD, Michael B. Brenner, MD, Laurie H. Glimcher, MD, Barton F. Haynes, MD, K. Frank Austen, MD, Allen C. Steere, MD, Darwin J. Prockop, MD, PhD, John P. Atkinson, MD, Douglas T. Fearon, MD, Robert J. Winchester, MD, Eng M. Tan, MD, Mart Mannik, MD, Dennis A. Carson, MD, Hugh O. McDevitt, MD,C. William Castor, MD, Joan A. Steitz, PhD, Michael Lerner, MD, PhD, and John A. Hardin, MD.

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