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Introduction
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This publication is made
possible by an educational grant from Amgen Inc. and Wyeth
Pharmaceuticals.
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Dietary Outcomes in Osteoarthritis Disease
Management
Carol J. Henderson, PhD, RD
Department of Nutrition
Georgia State University
Atlanta, GA
Summary Points
- Obesity is a risk factor for the development
and progression of osteoarthritis of the knee.
- There is information available from controlled
studies demonstrating improvement in pain, function, and possible reduction
in joint space narrowing in patients with OA if the knee is treated with
glucosamine sulfate.
- There continues to be a concern about the lack
of regulatory oversight of dietary supplements, thus there is no certainty
about the purity of the products, the dose, or the ingredients present.
Introduction
Osteoarthritis (OA) is the most common form of arthritis and is a major cause of
pain and physical disability in older adults. Whether dietary manipulation can
change the natural history of OA – including symptomatic profiles, functional
status, and structural integrity – remains a tantalizing possibility still
fraught with controversies.

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