Advertisement

secukinumab

 

Drug Class:

Biologics (IL-inhibitor)

Brand Names

Cosentyx


Dosages

Help

For ankylosing spondylitis: 150 mg by subcutaneous injection every 4 weeks with or without a loading dosage of 150 mg at weeks 0, 1, 2, 3, and 4.

For psoriatic arthritis: 150 mg by subcutaneous injection every 4 weeks with or without a loading dosage of 150 mg at weeks 0, 1, 2, 3, and 4. 

For psoriatic arthritis patients with coexistent moderate to severe plaque psoriasis: 300 mg by subcutaneous injection every 4 weeks with a loading dose of 300 mg by subcutaneous injection at Weeks 0, 1, 2, 3, and 4. NOTE: Each 300 mg dosage is given as 2 subcutaneous injections of 150 mg.


Potential Side Effects

Help

Caution should be used when prescribing secukinumab to patients with inflammatory bowel disease. Exacerbations, in some cases serious, occurred in secukinumab treated patients during clinical trials in plaque psoriasis, psoriatic arthritis and ankylosing spondylitis. In addition, new onset inflammatory bowel disease cases occurred in clinical trials with secukinumab. 


Special Instructions

Help
  • Women of childbearing age should use effective contraception during treatment.
  • Must be kept refrigerated. Do not freeze. Inject into thigh, abdomen or upper arm. Rotate injection sites. Do not inject where skin is tender, bruised, red or hard.

Be Aware

Help

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.

About Arthritis Today Drug Guide | Privacy Policy | Medical Review Panel

Advertisement
#
Advertisement
Advertisement