Drug Class:

NSAIDs (Cox-2 inhibitor)

Brand Names




For ankylosing spondylitis or OA: 200 mg once daily or 100 mg twice daily.

For RA: 100 or 200 mg twice per day.

Dosages for children: The dosages listed above are those typically prescribed for adults aged 18-65. Dosages for children can vary. Ask your

Potential Side Effects


Abdominal cramps, pain or discomfort; diarrhea; dizziness; drowsiness; gastrointestinal bleeding; headache; heartburn; high blood pressure; nausea or vomiting; peptic ulcer; swelling of feet; rash; ringing in the ears.

Special Instructions

  • Do not take with other prescription or over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs).

Be Aware

  • Celexcoxib may be used with low-dose aspirin, but doing so may slightly increase your risk of stomach ulcers. Tell your doctor if you have had a heart attack, stroke, angina, blood clot, hypertension, or sensitivity to aspirin or other NSAIDs.
  • Before taking any type of NSAID, tell your doctor if you drink alcohol or take blood thinners (including warfarin), ACE inhibitors, lithium or furosemide. Also report any sensitivity or allergy to aspirin or similar drugs. All non-aspirin NSAIDs may cause an increased risk of serious blood clots, heart attack and stroke, which can be fatal. This risk can occur as early as the first weeks using an NSAID and increases with dose and duration of use. Patients who have or who are at risk for cardiovascular disease are at greater risk for these complications than someone without cardiovascular disease or its risk factors. Treatment with NSAIDs following a first heart attack increases the risk of death in the first year after the heart attack (compared to not using NSAIDs after a first heart attack). NSAID use increases the risk of heart failure. NSAIDs should not be used for pain if you have had (or are about to have) coronary bypass surgery. Do not take NSAIDs late in pregnancy.

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.

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