Ehlers-Danlos syndromes (EDS) are a collection of genetic disorders that affect connective tissue. People who have EDS have problems with their collagen, a protein that adds strength and elasticity to connective tissue. This faulty collagen affects many body parts, including skin, muscles and ligaments. Each individual disorder in the collection of syndromes has a different set of symptoms. Treatment of EDS focuses on preventing damage to fragile body parts.