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Scleroderma


 
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What Is It?
What Are the Symptoms?
What Causes It?
How Is It Diagnosed?
Treatment Options
Who Is At Risk?
Resources and Suggestions
More Information About Scleroderma

What Is It?

Scleroderma (sclaire-row-DER-ma) is a disease that can cause thickening, hardening, or tightening of the skin, blood vessels and internal organs. Scleroderma is chronic, which means it can last a long time. There are two types of scleroderma:

  • Localized scleroderma mainly affects the skin. There are two types of localized scleroderma:
    • Morphia (hard, oval shaped patches on the skin. The patches usually are whitish with a purplish ring around them.)
    • Linear (lines or streaks of thickened skin in areas such as the arms, legs or forehead.)
  • Generalized scleroderma may affect many parts of the body. There are two types of generalized scleroderma:
    • Limited scleroderma occurs gradually and affects the skin and later may affect internal organs, such as esophagus, lungs or intestines.
    • Diffuse scleroderma develops more suddenly, with skin thickening throughout the body. Internal organs can also be affected.

What Are the Symptoms?

  • Skin changes:
    • Hardening and thickening
    • Ulcers or sores on fingers
    • Loss of hair over affected area
    • Change in skin color
    • Swelling/puffiness in fingers/toes
    • Skin appears shiny.
    • Usually skin creases disappear.
  • Difficulty making a fist
  • Sclerodactyly (hardness of toes/hands)
  • Raynaud's Phenomenon:
    • Poor blood flow to extremities.
    • Extremities are sensitive to cold caused by emotional stress.
    • Telangiectasia (tiny blood vessels seen at the surface of the skin).
    • Calcinosis (white calcium lumps under the skin)
  • Arthritis and muscle weakness
  • Sjogren's syndrome (dryness of eyes/mouth)
  • Digestive problems
  • Heart and lung problems
  • Kidney problems

What Causes It?

Although the cause is unknown, it is known that the body produces too much of a protein called collagen. Excess collagen is deposited causing thickening and hardening.

How Is It Diagnosed?

Physical exam, medical history and lab tests which may include biopsy and blood tests.

Treatment Options

Although there is no cure, many different drugs can help control it. Treatments may include:

  • Medications: NSAIDs/aspirin for inflammation and pain, steroids to treat muscle/joint problems, antacids to reduce heartburn, medication to control blood pressure and to increase blood flow
  • Exercise to improve overall health.
  • Joint protection to reduce stress on joints.
  • Skin protection to protect skin from injury.
  • Stress management - common with chronic disease.

Who Is At Risk?

The disease usually affects adults between the ages of 30 and 50, and more women than men.

More Information About Scleroderma

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