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Ankylosing Spondylitis
What Is It?
What Causes It?
What Are the Effects?
How Is It Diagnosed?
Treatment Options
Who Is At Risk?
Resources and Suggestions
More
Information
Información
en Español
What Is It?
Ankylosing Spondylitis (ANK-ki-low-sing spon-di-LIE-tis) is a chronic, or long-lasting,
disease that primarily affects the spine and may lead to stiffness of the back. The joints
and ligaments that normally permit the back to move become inflamed. The joints and bones
may grow (fuse) together.
What Causes It?
The cause is unknown but genetics seems to play a role. A gene called HLA-B27 occurs in
90 percent of those with ankylosing spondylitis. Just because you have the gene, does not
mean you will have ankylosing spondylitis. Other factors besides HLA-B27 are involved.
What Are the Effects?
- AS causes inflammation.
- Most common symptoms are chronic pain and stiffness in the lower back which usually
starts where the lower spine is joined to the pelvis, or hip.
How Is It Diagnosed?
- Medical history including symptoms
- X-rays
- Possibly blood tests for HLA-B27 gene
Treatment Options
With early diagnosis and treatment, pain and stiffness can be controlled and may reduce
fusing. In women, AS is usually mild and hard to diagnose. Treatments may include:
- Exercise
- Medications: NSAIDs, Sulfasalazine
- Posture management
- Self-help aids
- Surgery
Who Is At Risk?
Although
both men and women get ankylosing spondylitis, it primarily affects men. Onset
usually occurs between 17 and 35.
More
Information About Ankylosing Spondylitis
Resources and Suggestions
We Also Suggest:
- Consult your physician for appropriate diagnosis and treatment. Your local chapter can provide a listing of physicians who specialize in arthritis-related conditions.
- Learn to manage your condition -- get involved! Exciting events, volunteer activities and programs, such as the Arthritis Self-Help Course, support groups and exercise programs (consult your physician). Use the Chapter Locator to find activities near you.
- Arthritis Today magazine -- Search for more information or visit Your Arthritis Store to subscribe on-line!
- Your Arthritis Store -- books, newsletters, Arthritis Foundation membership, videos and more.
- Arthritis Today Drug Guide
- Alternative and Complementary Therapies
- Arthritis Today Supplement Guide
- Frequently asked questions about arthritis, treatments and coping skills.
- Arthritis in children, teens and young adults. Check out the information for parents and teachers, too!
- How to Care for Yourself
- Remember, you're not alone! Connect with other people on Message Boards.
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