Reprinted From Vol. 52, No. 1 of the Bulletin on the Rheumatic Diseases published by the Arthritis Foundation
Volume 52, Number 1
Christopher Wise, MD
Division of Rheumatology
Medical College of Virginia
Virginia Commonwealth University Health System Richmond, VA
Summary Points
Introduction
The injection of joints and periarticular structures with corticosteroids is commonly used by rheumatologists, orthopedists, and other practitioners to treat musculoskeletal pain. Few procedures in medical practice have the potential to be as effective in achieving symptomatic relief. Surveys have estimated that a majority of internists finishing their residency training feel a need for more training in these procedures.
In 1950, Hollander first reported transient improvement in patients with rheumatoid arthritis injected with cortisone. By the early 1960s, he had reported a series of more than 100,000 injections of joints, bursae, and tendon sheaths in patients (1). Aspiration and therapeutic injection of joints and periarticular tissues has become a common and essential part of rheumatology practice.
The evidence to support the efficacy of injections is mostly anecdotal or based on uncontrolled or retrospective observations.
In general, localized conditions are more amenable to injection than are generalized conditions, and inflammatory types of arthritis are more likely to benefit than noninflammatory or degenerative conditions.
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