Childhood Arthritis & Rheumatology Research Alliance

Through a partnership with the Arthritis Foundation, the Childhood Arthritis & Rheumatology Research Alliance (CARRA) established a national organization of pediatric rheumatologists to answer critical clinical research questions. Since our launch in 2001, we have been committed to advancing the health and quality of life of children living with rheumatic disease and arthritis.


CARRA is a multi-center network of pediatric rheumatology research centers across North America that works together on comparative-effectiveness research and quality improvement research. The advantage of such collaboration is that it increases the number of children who participate in studies and reduces the time it takes researchers to reach valuable conclusions. By creating, sharing and conserving a unified infrastructure, the Alliance assures that investments in pediatric rheumatology research are used efficiently and for the highest priority health issues.

In 2010 CARRA introduced CARRA-net, a registry of people with the various forms of juvenile arthritis, including juvenile idiopathic arthritis, childhood lupus and childhood scleroderma. The registry will allow long-term monitoring of a child’s disease and response to treatment, even when he or she changes medications or physicians.

CARRA members will work together to conduct efficient, results-oriented clinical research and treatment trials. Our collective goal is to improve the health and health outcomes of children who live with rheumatic diseases. Sharing patient data and a unified infrastructure, the Arthritis Foundation’s partnership with CARRA provides an accessible point of entry for patients and families across the United States and Canada to participate in research studies and trials of new therapies.

More than three-quarters of North America's pediatric rheumatologists are represented in CARRA. The Alliance is currently led by a committee of members from eight medical centers in the United States and Canada. The office is located at Stanford University. Along with the Foundation’s ongoing support of CARRA and our funding of specific research projects using the Alliance’s network, CARRA has also received generous financial support from the National Institutes of health, the Wasie Foundation, the American College of Rheumatology, Lucile Packard Foundation for Children's Health, Barr Laboratories and Pfizer, Incorporated.

If you would like your child to be included in the CARRA registry of people with juvenile arthritis, please contact your pediatric rheumatologist or rheumatologist. To learn more about CARRA and the research studies conducted through its network, visit the CARRA website and the CARRA-net website.

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